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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CLNS1A
All Species:
14.55
Human Site:
S6
Identified Species:
22.86
UniProt:
P54105
Number Species:
14
Phosphosite Substitution
Charge Score:
-0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P54105
NP_001284.1
237
26215
S6
_
_
M
S
F
L
K
S
F
P
P
P
G
P
A
Chimpanzee
Pan troglodytes
XP_001175048
222
24569
Rhesus Macaque
Macaca mulatta
XP_001088333
203
22330
Dog
Lupus familis
XP_535567
226
24585
Cat
Felis silvestris
Mouse
Mus musculus
Q61189
236
26003
S6
_
_
M
S
F
L
K
S
F
P
P
P
G
S
A
Rat
Rattus norvegicus
Q04753
236
26074
S6
_
_
M
S
F
L
K
S
F
P
P
P
G
S
A
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001519221
278
30242
S11
V
A
G
T
V
V
S
S
G
V
H
L
R
E
V
Chicken
Gallus gallus
XP_423253
238
26615
R6
_
_
M
S
F
L
K
R
F
P
P
P
D
D
G
Frog
Xenopus laevis
P54106
241
26428
S6
_
_
M
N
L
L
S
S
F
P
P
P
A
D
G
Zebra Danio
Brachydanio rerio
NP_571499
249
27316
S6
_
_
M
V
L
L
K
S
L
P
P
P
S
E
G
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_611237
215
23724
Honey Bee
Apis mellifera
XP_624081
207
23224
Nematode Worm
Caenorhab. elegans
NP_001021287
205
22895
Sea Urchin
Strong. purpuratus
XP_001194575
165
18108
Poplar Tree
Populus trichocarpa
XP_002318279
231
25740
Q7
_
M
A
P
G
L
R
Q
F
T
E
R
R
G
D
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
93.2
85.6
82.2
N.A.
90.3
90.3
N.A.
40.6
82.3
72.1
68.2
N.A.
20.2
40
29.9
24.4
Protein Similarity:
100
93.2
85.6
85.2
N.A.
94.9
94.9
N.A.
53.2
90.3
82.5
80.3
N.A.
37.5
56.5
45.5
40.9
P-Site Identity:
100
0
0
0
N.A.
92.3
92.3
N.A.
6.6
69.2
53.8
53.8
N.A.
0
0
0
0
P-Site Similarity:
100
0
0
0
N.A.
92.3
92.3
N.A.
20
69.2
61.5
53.8
N.A.
0
0
0
0
Percent
Protein Identity:
25.7
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
48.1
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
14.2
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
21.4
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
7
7
0
0
0
0
0
0
0
0
0
7
0
20
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
0
7
14
7
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
7
0
0
14
0
% E
% Phe:
0
0
0
0
27
0
0
0
40
0
0
0
0
0
0
% F
% Gly:
0
0
7
0
7
0
0
0
7
0
0
0
20
7
20
% G
% His:
0
0
0
0
0
0
0
0
0
0
7
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
34
0
0
0
0
0
0
0
0
% K
% Leu:
0
0
0
0
14
47
0
0
7
0
0
7
0
0
0
% L
% Met:
0
7
40
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
7
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
7
0
0
0
0
0
40
40
40
0
7
0
% P
% Gln:
0
0
0
0
0
0
0
7
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
7
7
0
0
0
7
14
0
0
% R
% Ser:
0
0
0
27
0
0
14
40
0
0
0
0
7
14
0
% S
% Thr:
0
0
0
7
0
0
0
0
0
7
0
0
0
0
0
% T
% Val:
7
0
0
7
7
7
0
0
0
7
0
0
0
0
7
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
47
40
0
0
0
0
0
0
0
0
0
0
0
0
0
% _